A project targeted enhanced health treatment provision by concentrating on the design of catheters. The aim of the research had been to develop enhanced design principles for catheters that reduce medical problems and patient discomfort. Many health procedures need the use of catheters either in bloodstream vessels or the urinary tract. Nevertheless, this can end up in clinical complications because well as patient discomfort. Scientists set out to develop advanced design strategies for catheter-based medical products. The key goal had been to reduce catheter-mediated complications. To achieve their objectives, a number of solutions for enhanced catheter design had been examined. They included improved catheter geometry and texture, advanced coatings and ways of calculating and minimizing the forces acting between the catheter and the human structure. In purchase to test the improvements it had been necessary to develop appropriate human structure models. Researchers found that currently-available synthetic tissue models were not capable of mimicking individual structure sufficiently. For this explanation, many tests had been carried off using an ex vivo porcine aorta model to simulate the interaction of the catheter using the structure it comes into contact with. A series of in-house catheter designs had been tested alongside specially-designed holders for the catheters and structure. Furthermore, scientists evaluated the skin friction behavior and tensile power using ex vivo human skin, individual dermis and tissue-engineered skin. Histological analysis alongside different spectroscopic and microscopic analyses had been performed to better comprehend the mechanical response of human being tissue to real interactions and the subsequent muscle harm. The friction behaviour had been also examined for in vivo human epidermis as well as porcine epidermis and synthetic skin models. To minimise the side-effects of catheterisation, the task developed improved polymer coatings for health products. These coatings are capable of interacting with water, and are lubricious and anti-bacterial to reduce structure damage and infection, correspondingly.